Anti-CD31抗體,血小板內皮細胞黏附分子1抗體科研產品介紹：
[FUNCTION]Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Isoform Delta15 is unable to protect against apoptosis. Modulates BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC).
與“Anti-CD31抗體,血小板內皮細胞黏附分子1抗體科研"有關的產品：
小鼠抗*受體(ATR)試劑盒說明書，96T/48T代測
小鼠*受體(TR)試劑盒說明書，96T/48T代測
小鼠心肌肌鈣蛋白Ⅰ(cTn-Ⅰ)試劑盒說明書，96T/48T代測
小鼠磷酸肌醇3激酶(PI3K)試劑盒說明書，96T/48T代測
小鼠蛋白激酶B(PKB)試劑盒說明書，96T/48T代測
小鼠分泌型免疫球蛋白A(sIgA)試劑盒說明書，96T/48T代測
小鼠血紅素氧合酶2(HO-2)試劑盒說明書，96T/48T代測
小鼠骨膠原交聯(Cr)試劑盒說明書，96T/48T代測
小鼠Ⅰ型前膠原C末端肽(CⅠCP)試劑盒說明書，96T/48T代測
小鼠脫氧吡啶酚/脫氧吡啶啉(DPD)試劑盒說明書，96T/48T代測
產品詳情：
產品編號：HRK-0468R
產品規格: 0.1ml/0.2ml
產品別名：plaet endothelial cell adhesion molecule precursor-1; PECAM-1; PECAM1; Adhesion molecule; CD31 antigen; CD31 EndoCAM; Endocam; FLJ34100; FLJ58394; GPIIA; Pecam 1; PECA1_HUMAN; PECAM 1 CD31 EndoCAM; PECA1; Pecam1; Plaet endothelial cell adhesion molecule; Plaet/endothelial cell adhesion molecule 1; Adhesion molecule; Plaet/endothelial cell adhesion molecule
產品價格：詢價(電詢或客服)
產品用途：科研實驗
貯 存： 貯存于-20℃.
與“"有關的其他產品：
Anti-Dengue Virus（Dengue virus type -2） 抗登革熱病毒抗體
Anti-polyprotein(duck hepatitis A virus, DHAV) 鴨甲型肝炎A病毒抗體
Anti-Des(Desmin) 結蛋白抗體
Anti-DISC1（disrupted in schizophrenia1）(CT) DISC1 C端抗體
Anti-DISC1（disrupted in schizophrenia1）（NT） DISC1 N端抗體
Anti-DLK1(Delta like 1 homolog) 穿膜蛋白DLK1抗體
Anti-DLX4 (Dsital-less homebox4 isoformα/β) 兔抗DLX4抗體
Anti-DKK1(Dickkopf 1) 抑癌蛋白DKK1抗體
