熒光素標(biāo)記巴爾得-別德爾綜合征相關(guān)蛋白10抗體,Anti-BBS10-FITC抗體產(chǎn)品詳情：
概念
抗體經(jīng)過酶標(biāo)記、鐵蛋白標(biāo)記或通過膠體金標(biāo)記獲得標(biāo)記抗體，是免疫電鏡樣品制備的一種方法，用于觀察抗原抗體免疫復(fù)合物方面研究的手段。免疫標(biāo)記技術(shù)是將一些既易測定又具有高度敏感性的物質(zhì)標(biāo)記到特異性抗原或抗體分子上，通過這些標(biāo)記物的增強(qiáng)放大效應(yīng)來顯示反應(yīng)系統(tǒng)中抗原或抗體的性質(zhì)與含量。抗體標(biāo)記主要是用于抗原的定位分析，在某些情況下，也可以對混雜有大量其他分子的樣本中的抗原進(jìn)行定量檢測。由于抗體與其相應(yīng)抗原具有很高的親和力，因此帶有易識別標(biāo)記物的抗體可以定位分析抗原，并且是一種理想的快速價廉的定量測定方法。
熒光色素是zui常用于標(biāo)記抗體的標(biāo)記物之一。熒光素經(jīng)恰當(dāng)?shù)募ぐl(fā)可發(fā)光，從而得知抗體的定位和待測抗原的分布情況，主要用于細(xì)胞分選或高分辨率免疫染色，是一種非常好的亞細(xì)胞水平精確定位的方法
【產(chǎn)品名稱】：熒光素標(biāo)記TBR1蛋白抗體,Anti-TBR1-FITC抗體
【產(chǎn)品編號】：HRK-11603R-FITC
【規(guī) 格】：100ug
【產(chǎn)品別名】：A novel murine and human gene, TBR-1, encodes a putative transcription factor related to the Brachyrury (T) gene that is expressed only in postmitotic cells. T-brain-1 (TBR-1) mRNA is largely restricted to the cerebral cortex, where, during embryogenesis, it defines different regions that give rise to the palecortex, limbic cortex and neocortex (1-3). TBR-1, Pax-6 and Emx-1 are expressed in the mouse and chicken pallium. The pallio-subpallial boundary lies at the interface between the TBR-1 and Dlx-2 expression domains. Chicken genes homolgous to these mouse genes are expressed in topologically comparable patterns during development, suggesting that mouse and chicken may have similar histogenetic specification processes and field homologies (4). CASK/LIN-2, a membrane-associated guanylate kinase, is required for EGFR localization and signaling. In adult rat brain, CASK is concentrated at neuronal synapses and binds to the cell-surface proteins. CASK can interact with TBR-1, which is involved in forebrain development. CASK enters into the nucleus and binds to a specific DNA sequence (the T-element) in a complex with TBR-1. Thus, CASK acts as a coactivator of TBR-1 to induce transcription of T-element containing genes, including reelin (5); TBR1_HUMAN.
【抗體來源】：Rabbit
【產(chǎn)品類型】：標(biāo)記抗體
【性 狀】：Lyophilized or Liquid
【亞 型】：IgG
【純化方法】：affinity purified by Protein A
【儲 存 液】：0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
【保存條件】：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
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